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The downside to fibrates, however, is that they cannot match statins’ ability to lower LDL Amla, another name for Indian Gooseberry, may be one of the strongest natural alternatives for lowering total and LDL cholesterol, raising HDL cholesterol, and lowering inflammation. What you will need to eat are soy proteins like tofu or soy milk, oats and barley for the sticky soluble fiber, plant sterol ester-enriched margarine, and almonds and walnuts. Common Side Effects of Statins. Cholesterol absorption inhibitor drugs, such as Zetia, work by blocking the absorption of cholesterol from food in the small intestine into the bloodstream. PCSK9 inhibitors, such as Repatha, work by blocking an enzyme that breaks down LDL receptors in the liver. It is vitamin B3, so people can also find this product over the counter. Usually, these medications are used in combination with statins to treat high cholesterol, but they can also be taken independently. 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Experts said Repatha and Praluent are the first in an 'exciting' new class of treatments that halve levels of 'bad' cholesterol with few side-effects. Natural Alternatives to Statins: Foods That Help Lower Cholesterol. Statins are used to lower cholesterol, but some people have side effects or don’t want to take meds. Zetia is often prescribed as an alternative to statin drugs when patients experience severe side effects. Lower back or side pain, tenderness around the eyes or cheekbones.. According to Harvard Health, only atorvastatin and rosuvastatin (Crestor) are as effective as fibrates in this area. Omega3-rich foods, such as fatty fish. Furthermore, fibrates are often quite successful in raising HDL levels (high-density lipoprotein, or “good” cholesterol). These LDL receptors remove LDL particles from the blood “Pfizer says an over-the-counter Lipitor would help close a ‘treatment gap’ for people at risk of heart attacks and strokes who don’t currently take a statin. Simvastatin (Zocor) at 20-40 mg daily, Pravastatin (Pravachol) at 40-80 mg daily, Lovastatin (Mevacor) at 40 mg daily, and Fluvastatin at 40 mg twice daily are other examples. Find out about alternatives and their effectiveness. The European Union, China and Russia have decided certain drugs have no place in agriculture. ” In theory this would save money in the long run by getting more people on statins and “warding off costly health problems down the line. Side effects of these medications are back pain, muscle pain, and cold symptoms The newest class of cholesterol lowering drugs, PCSK9 inhibitors, have proven to be quite effective in lowering high LDL levels without statins. Atorvastatin Alternatives Compared Atorvastatin Zetia (ezetimibe) Praluent (alirocumab) Prescription only Atorvastatin is effective at lowering cholesterol; however, its use may be limited by side effects such as muscle pain. 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