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Hold the device upright between your thumb and first 2 fingers. Imitrex NasalSpray is a prescription medicine used to treat the symptoms of migraine headache and cluster headache. After using Imitrex: If your headache does not completely go away, or goes away and comes back, use a second dose if it has been at least 2 hours since your first dose. Tilt your head back slightly Intranasal Route Imitrex and Generic Equivalents Nasal Spray Intranasal absorption of Imitrex nasal spray and generic equivalents is rapid with a peak concentration of sumatriptan achieved within 1 to 1. Call your doctor right away if you have weakness on 1 side of the body, trouble speaking or thinking, change in balance, drooping on 1 side of the face, or change in eyesight. The 5-mg and 20-mg doses are given as a single spray in 1 nostril What is Imitrex Nasal Spray and how is it used? Imitrex Nasal Spray is an antimigraine agent, seratonin 5-HT-Receptor agonist Very bad and sometimes deadly brain blood vessel problems like stroke have rarely happened with Imitrex (sumatriptan nasal spray). Insert half of the spray nozzle into the open nostril and angle outward. To use the nasal spray: Gently blow your nose to clear the nostrils before you use this medicine. Take a Imitrex tablet whole with a full glass of water. Gently press one nostril to close it. To view step-by-step instructions for using Imitrex nasal spray, see the drug’s instructions. If you are 65 or older, use Imitrex. Never use more than your recommended dose Place the nozzle of the spray device into the other nostril and breathe in gently as you press the plunger. * To take a 10-mg dose of Imitrex nasal spray, you’ll use two 5-mg nasal spray devices, one in each nostril. However, perform a cardiac evaluation if these patients are at high cardiac risk. Only 3% of the dose is renally eliminated as unchanged drug, with 42% eliminated as the major metabolite.. Imitrex Nasal Spray may be used alone or with other medications. The recommended adult dose of Imitrex Nasal Spray for the acute treatment of migraine is 5 mg, 10 mg, or 20 mg. The 20-mg dose may provide a greater effect than the 5-mg and 10-mg doses, but may have a greater risk of adverse reactions [see Clinical Studies (14)]. The use of IMITREX nasal spray is contraindicated how do you get imitrex in patients with CAD and those with Prinzmetal’s variant angina For Imitrex nasal spray, you’ll insert the unit (disposable device) in one nostril and spray one time. Dosage for cluster headaches Only the Imitrex injection is used to treat cluster. Keep your head upright, remove the nozzle from your nose, and gently breathe in through. May occur after treatment with IMITREX nasal spray and are usually non-cardiac in origin.